The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration Journal of Neuroinflammation Springer Nature Link biochemistry Why is the Pentose Phosphate Pathway so active in erythrocytes? Biology Stack Exchange Glucose metabolism begins with its transport into cells via GLUT transporters, where it is phosphorylated to glucose 6 phosphate (Glucose 6 P). This molecule can enter various pathways, including the pentose phosphate pathway or hexosamine biosynthesis. Pentose Phosphate Pathway ChemTalk Pentose Phosphate Pathway on the MCAT MedLife Mastery